Cannabinoids

Ebook
On sale Feb 17, 2026 | 232 Pages | 9780262051477

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The mysteries of the brain’s own cannabinoid system exposed and explained.

Though cannabis has been used, for pain or pleasure, for over 4000 years, only lately have we learned, first, what makes it work and, more recently, how. Unraveling the mystery of the human brain’s special relationship with a psychoactive chemical derived from a plant—tetrahydrocannabinol, or THC, specifically—neuroscientist Linda Parker recounts the discovery of the brain’s own THC, called endocannabinoids, and describes the remarkable brain chemical system this discovery revealed.

In expert yet accessible terms, Cannabinoids explains what we know about this system, how it functions, and how it interacts with the plant materials in cannabis. Parker explores the role of the endocannabinoid system in regulating emotion, anxiety, depression, psychosis, learning, memory, feeding, nausea, pain, epilepsy, and neurological disorders—as well as, naturally, the brain’s reward system. Examining the link between anecdotal reports and the current scientific literature, the book offers a balanced presentation of the scientific evidence for the medicinal use of marijuana, providing a timely intervention in ongoing debates about cannabis’s medicinal value and its legal status.
Series Foreword
Preface
1 Introduction to Cannabis
2 Discovery of THC and the Endocannabinoid System
3 Constituents of Cannabis
4 Cannabinoids and Addiction
5 Cannabinoids and Emotional Regulation
6 Cannabinoids and Cognition/Brain Development
7 Cannabinoids Feeding, Body Weight and Appetite
8 Cannabinoids and Nausea and Vomiting
9 Cannabinoids and Pain
10 Cannabinoids and Neurological Disorders
11 Conclusions and What’s Next
Acknowledgments
Glossary
Notes
Bibliography
Further Reading
Index
Linda A. Parker is University Faculty Emeritus and former Canada Research Chair in Behavioral Neuroscience at the University of Guelph, Ontario, Canada.

About

The mysteries of the brain’s own cannabinoid system exposed and explained.

Though cannabis has been used, for pain or pleasure, for over 4000 years, only lately have we learned, first, what makes it work and, more recently, how. Unraveling the mystery of the human brain’s special relationship with a psychoactive chemical derived from a plant—tetrahydrocannabinol, or THC, specifically—neuroscientist Linda Parker recounts the discovery of the brain’s own THC, called endocannabinoids, and describes the remarkable brain chemical system this discovery revealed.

In expert yet accessible terms, Cannabinoids explains what we know about this system, how it functions, and how it interacts with the plant materials in cannabis. Parker explores the role of the endocannabinoid system in regulating emotion, anxiety, depression, psychosis, learning, memory, feeding, nausea, pain, epilepsy, and neurological disorders—as well as, naturally, the brain’s reward system. Examining the link between anecdotal reports and the current scientific literature, the book offers a balanced presentation of the scientific evidence for the medicinal use of marijuana, providing a timely intervention in ongoing debates about cannabis’s medicinal value and its legal status.

Table of Contents

Series Foreword
Preface
1 Introduction to Cannabis
2 Discovery of THC and the Endocannabinoid System
3 Constituents of Cannabis
4 Cannabinoids and Addiction
5 Cannabinoids and Emotional Regulation
6 Cannabinoids and Cognition/Brain Development
7 Cannabinoids Feeding, Body Weight and Appetite
8 Cannabinoids and Nausea and Vomiting
9 Cannabinoids and Pain
10 Cannabinoids and Neurological Disorders
11 Conclusions and What’s Next
Acknowledgments
Glossary
Notes
Bibliography
Further Reading
Index

Author

Linda A. Parker is University Faculty Emeritus and former Canada Research Chair in Behavioral Neuroscience at the University of Guelph, Ontario, Canada.

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