A comprehensive review of the scientific literature on the possible benefits of CBD, describing findings from both preclinical and human clinical studies.

CBD (cannabidiol), a nonintoxicating compound derived from the cannabis plant, can be found in products ranging from lotion and smoothies to chewable gummies and pet treats. It’s been promoted—but not always scientifically validated—as a treatment for medical conditions including psychosis, anxiety, pain, and even cancer. This book by three leading cannabis researchers looks at the science of CBD. It offers a comprehensive review of the scientific literature on the possible benefits of CBD, describing findings from both preclinical and human clinical studies. 
 
The authors report that the current CBD fad has some basis in preclinical animal research that indicates potential beneficial effects. Clinical studies, hampered by regulations governing research with cannabis, have lagged behind the basic animal research. The authors examine what research shows about chemical and pharmacological aspects of CBD and CBD’s interaction with THC, the main psychotropic compound found in cannabis. They go on to review current state of knowledge about CBD’s effectiveness in treating epilepsy, cancer, nausea, pain, anxiety, PTSD, depression, sleep disorders, psychosis, and addiction.
 
Preface vii
1 Introduction 1
2 Chemical and Pharmacological Aspects 11
3 CBD/THC Interactions 39
4 Epilepsy 53
5 Neuroprotection, Tissue Protection, and Cancer 63
6 Nausea, Vomiting, and Appetite 97
7 Pain and Inflammation 117
8 Anxiety 149
9 PTSD, Depression and Sleep 163
10 Psychosis and Schizophrenia 181
11 Addiction 195
12 Conclusion 207
References 221
Index 301
Linda A. Parker is Professor Emeritus in the Psychology and Collaborative Neuroscience Program at the University of Guelph and the author of Cannabinoids and the Brain (MIT Press).
 
Erin M. Rock is a Postdoctoral Fellow and Adjunct Faculty member in the Psychology and Collaborative Neuroscience Program at the University of Guelph. 
 
Raphael Mechoulam, often called “the father of cannabis research,” is Lionel Jacobson Professor of Medicinal Chemistry at Hebrew University and winner of the 2019 Harvey Prize for outstanding contributions to science and technology.
 

About

A comprehensive review of the scientific literature on the possible benefits of CBD, describing findings from both preclinical and human clinical studies.

CBD (cannabidiol), a nonintoxicating compound derived from the cannabis plant, can be found in products ranging from lotion and smoothies to chewable gummies and pet treats. It’s been promoted—but not always scientifically validated—as a treatment for medical conditions including psychosis, anxiety, pain, and even cancer. This book by three leading cannabis researchers looks at the science of CBD. It offers a comprehensive review of the scientific literature on the possible benefits of CBD, describing findings from both preclinical and human clinical studies. 
 
The authors report that the current CBD fad has some basis in preclinical animal research that indicates potential beneficial effects. Clinical studies, hampered by regulations governing research with cannabis, have lagged behind the basic animal research. The authors examine what research shows about chemical and pharmacological aspects of CBD and CBD’s interaction with THC, the main psychotropic compound found in cannabis. They go on to review current state of knowledge about CBD’s effectiveness in treating epilepsy, cancer, nausea, pain, anxiety, PTSD, depression, sleep disorders, psychosis, and addiction.
 

Table of Contents

Preface vii
1 Introduction 1
2 Chemical and Pharmacological Aspects 11
3 CBD/THC Interactions 39
4 Epilepsy 53
5 Neuroprotection, Tissue Protection, and Cancer 63
6 Nausea, Vomiting, and Appetite 97
7 Pain and Inflammation 117
8 Anxiety 149
9 PTSD, Depression and Sleep 163
10 Psychosis and Schizophrenia 181
11 Addiction 195
12 Conclusion 207
References 221
Index 301

Author

Linda A. Parker is Professor Emeritus in the Psychology and Collaborative Neuroscience Program at the University of Guelph and the author of Cannabinoids and the Brain (MIT Press).
 
Erin M. Rock is a Postdoctoral Fellow and Adjunct Faculty member in the Psychology and Collaborative Neuroscience Program at the University of Guelph. 
 
Raphael Mechoulam, often called “the father of cannabis research,” is Lionel Jacobson Professor of Medicinal Chemistry at Hebrew University and winner of the 2019 Harvey Prize for outstanding contributions to science and technology.
 

Books for National Depression Education and Awareness Month

For National Depression Education and Awareness Month in October, we are sharing a collection of titles that educates and informs on depression, including personal stories from those who have experienced depression and topics that range from causes and symptoms of depression to how to develop coping mechanisms to battle depression.

Read more

Horror Titles for the Halloween Season

In celebration of the Halloween season, we are sharing horror books that are aligned with the themes of the holiday: the sometimes unknown and scary creatures and witches. From classic ghost stories and popular novels that are celebrated today, in literature courses and beyond, to contemporary stories about the monsters that hide in the dark, our list

Read more

Books for LGBTQIA+ History Month

For LGBTQIA+ History Month in October, we’re celebrating the shared history of individuals within the community and the importance of the activists who have fought for their rights and the rights of others. We acknowledge the varying and diverse experiences within the LGBTQIA+ community that have shaped history and have led the way for those

Read more